Software
Open tools for statistical genetics.
fastGxE
Genome-wide detection of genotype–environment (G×E) interactions at biobank scale with fastGxE. A fast and scalable method for genome-wide GxE analysis in large-scale data.
Chao Ning, Xiang Zhou. Nature Genetics, 2026.
GenSep
Quantifying the genetic separability of disease subtypes. Estimates how well genetics can tell two subtypes apart (genetic separation variance and case–case AUC, with standard errors) from GWAS summary statistics or heritability and genetic-correlation estimates.
Chao Ning, Jasper Hof, Doug Speed. medRxiv, 2026.
mmSuSiE
A Python package for mixed-model SuSiE fine-mapping. Integrates linear mixed models with the Sum of Single Effects (SuSiE) framework to fine-map causal variants while accounting for population structure and relatedness.